Abstract
Spiroplasma species are organisms that normally colonize plants and insects. We describe the first case of human systemic infection caused by Spiroplasma bacteria in a patient with hypogammaglobulinemia undergoing treatment with biological disease-modifying antirheumatic agents. Spiroplasma turonicum was identified through molecular methods in several blood cultures. The infection was successfully treated with doxycycline plus levofloxacin.
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MeSH terms
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Agammaglobulinemia / chemically induced
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Agammaglobulinemia / complications*
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Aged
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Anti-Bacterial Agents / therapeutic use
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Blood / microbiology*
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DNA, Bacterial / chemistry
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DNA, Bacterial / genetics
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Doxycycline / therapeutic use
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Female
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Gram-Negative Bacterial Infections / diagnosis*
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Gram-Negative Bacterial Infections / drug therapy
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Gram-Negative Bacterial Infections / microbiology*
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Humans
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Levofloxacin / therapeutic use
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Microbiological Techniques
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Molecular Sequence Data
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Sepsis / diagnosis*
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Sepsis / drug therapy
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Sepsis / microbiology*
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Sequence Analysis, DNA
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Spiroplasma / isolation & purification*
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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Levofloxacin
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Doxycycline