Identification and characterization of carbapenemase genes in clinical isolates of carbapenem-resistant Acinetobacter Baumannii from general hospital in Thailand

Southeast Asian J Trop Med Public Health. 2014 Jul;45(4):874-80.

Abstract

This study identified, using PCR blaoxA,,23 encoding carbapenamase OXA-23 in 42 carbapenem-resistant Acinetobacter baumannii (CRAB) clinical iso- lates and blaOXA-40-like encoding carbapenamase OXA-40-like in one isolate (the first such Thai sample) obtained from patients admitted to Hua Hin Hospital, Thailand during November 2011-September 2012. Using repetitive extragenic palindromic PCR, the isolates could be divided into 4 different clones, with 40 isolates belonging to clone A and the remaining to B, C and D. Other resistance in CRAB needs to be investigated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter baumannii / isolation & purification*
  • Bacterial Proteins / genetics*
  • Carbapenems / pharmacology
  • Drug Resistance, Bacterial / genetics*
  • Genes, Bacterial
  • Hospitals, General
  • Humans
  • Microbial Sensitivity Tests
  • Polymerase Chain Reaction
  • Thailand / epidemiology
  • beta-Lactamases / genetics*

Substances

  • Bacterial Proteins
  • Carbapenems
  • beta-Lactamases
  • carbapenemase