Abstract
Three indole alkaloid glycosides, strobilanthosides A-C (1-3), two known indole alkaloid glucosides (4 and 5), and five phenylethanoid glycosides (8-10) were isolated from the aerial parts of Strobilanthes cusia. The structures of the new compounds were elucidated by spectrometric analysis, and the absolute configurations of 1 and 2 were established by ECD spectrocsopy. N'-β-d-Glucopyranosylindirubin (5) showed weak antibacterial activity (MIC 62.5-125 μM) against Staphylococcus aureus.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acanthaceae / chemistry*
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification*
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Anti-Bacterial Agents / pharmacology
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / isolation & purification*
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Drugs, Chinese Herbal / pharmacology
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Glycosides / chemistry
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Glycosides / isolation & purification*
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Glycosides / pharmacology
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Indole Alkaloids / chemistry
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Indole Alkaloids / isolation & purification*
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Indole Alkaloids / pharmacology
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Microbial Sensitivity Tests
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Staphylococcus aureus / drug effects
Substances
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Anti-Bacterial Agents
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Drugs, Chinese Herbal
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Glycosides
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Indole Alkaloids
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strobilanthoside A
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strobilanthoside B
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strobilanthoside C