The effect of preoperative skin preparation products on surgical site infection

Infect Control Hosp Epidemiol. 2014 Dec;35(12):1535-8. doi: 10.1086/678601. Epub 2014 Nov 7.

Abstract

Skin preparation products contribute to surgical site infection (SSI) prevention. In a case-control study, diabetes was associated with increased SSI (adjusted odds ratio [OR], 5.74 [95% confidence interval (CI), 1.22-27.0]), while the use of chlorhexidine gluconate (CHG) plus isopropyl alcohol versus CHG alone was found to be protective (adjusted OR, 2.64 [95% CI, 1.12-6.20]).

MeSH terms

  • 2-Propanol / pharmacology*
  • Adult
  • Anti-Infective Agents, Local / pharmacology
  • Case-Control Studies
  • Chlorhexidine / pharmacology*
  • Colorado
  • Disinfection / methods*
  • Electronic Health Records
  • Female
  • Humans
  • Male
  • Middle Aged
  • Preoperative Care / methods
  • Risk Factors
  • Surgical Procedures, Operative / adverse effects*
  • Surgical Procedures, Operative / classification
  • Surgical Wound Infection* / epidemiology
  • Surgical Wound Infection* / prevention & control
  • Treatment Outcome

Substances

  • Anti-Infective Agents, Local
  • 2-Propanol
  • Chlorhexidine