Abstract
An efficient one-pot synthesis of various 2,3-dihydroquinazolin-4(1H)-one derivatives was accomplished using Cu(OTf)2-catalyzed multi-component reactions between isatoic anhydride, ketones, and amines. The method has several significant advantages; mild reaction conditions, easy handling, and efficiency of catalyst.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amines / chemistry
-
Chemistry Techniques, Synthetic
-
Copper / chemistry*
-
Ketones / chemistry
-
Mesylates / chemistry*
-
Models, Molecular
-
Oxazines / chemistry
-
Quinazolinones / chemical synthesis*
-
Quinazolinones / chemistry*
Substances
-
Amines
-
Ketones
-
Mesylates
-
Oxazines
-
Quinazolinones
-
Copper
-
trifluoromethanesulfonic acid
-
isatoic anhydride