New maltol glycosides from Flos Sophorae

J Nat Med. 2015 Apr;69(2):249-54. doi: 10.1007/s11418-014-0877-1. Epub 2014 Nov 15.

Abstract

Three new maltol glycosides, designated soyamalosides A (1), B (2), and C (3), together with eight known compounds (4-11), were obtained from a 70 % EtOH extract of Flos Sophorae. Their structures were elucidated by chemical and spectroscopic methods. Of the known compounds, this is the first report of 4-6, 9, and 11 in the Sophora genus. Compounds 2, 3, and 10 showed significant protective effects against antimycin A-induced L6 cell injury.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antimycin A
  • Drugs, Chinese Herbal / chemistry*
  • Flowers / chemistry*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Molecular Structure
  • Protective Agents / chemistry
  • Protective Agents / isolation & purification
  • Protective Agents / pharmacology
  • Pyrones / chemistry
  • Pyrones / isolation & purification
  • Pyrones / pharmacology
  • Sophora / chemistry*

Substances

  • Drugs, Chinese Herbal
  • Glycosides
  • Protective Agents
  • Pyrones
  • soyamaloside A
  • soyamaloside B
  • soyamaloside C
  • maltol
  • Antimycin A