Cord blood full blood count parameters in Lagos, Nigeria

Pan Afr Med J. 2014 Mar 13:17:192. doi: 10.11604/pamj.2014.17.192.3680. eCollection 2014.

Abstract

Introduction: Full blood count (FBC), one of the most frequently requested for laboratory investigations, is a simple, fast and cheap test and is a reliable indicator of health. Due to its usefulness in the assessment of health status of individuals, its parameters in cord blood, a major source of haemopoietic stem cell transplantation and an ideal source for laboratory investigations for newborns were determined to provide a useful guide to local neonatologists and stem cell transplant physicians.

Methods: Three millilitres of umbilical cord blood was collected from 130 normal birth weight newborns (69 males and 61 females) whose cord were clamped immediately after delivery, at a teaching hospital in Lagos, Nigeria and full blood count parameters were determined using Sysmex autoanalyzer, model KX-21N. Consented mothers of the newborns were selected based on, age between 18 and 45 years; uneventful pregnancy and delivery and haemoglobin (Hb) concentration ≥ 10 g/dL.

Results: There were no statistical gender differences in the mean values of Hb concentrations (M = 13.27 ±1.60 g/dL; F = 13.32±1.61g/dL; p = 0.93), total white cell count (M = 3.16±5.43 × 10(9)/L; F = 13.07±4.98 × 10(9)/L; p= 0.92), platelet count (M= 223.64± 64.21 × 10(9)/L; F = 226.69±80.83 × 10(9)/L; p = 0.81) and other parameters.

Conclusion: Mean values of full blood count parameters obtained in this study are comparable to reports from other studies in developing countries and could be a useful guide for neonatologists and stem cell transplant physicians in our geographical location.

Keywords: Haemoglobin; cord blood; neonatologist; stem cell; umbilical cord.

MeSH terms

  • Adolescent
  • Adult
  • Blood Cell Count*
  • Female
  • Fetal Blood / cytology*
  • Hemoglobins / metabolism*
  • Humans
  • Infant, Newborn
  • Leukocyte Count
  • Male
  • Middle Aged
  • Nigeria
  • Platelet Count
  • Pregnancy
  • Young Adult

Substances

  • Hemoglobins