Abstract
There is an unmet need for a consistent set of tools for the evaluation of 3D-printed constructs. A toolbox developed to design, characterize, and evaluate 3D-printed poly(propylene fumarate) scaffolds is proposed for vascularized engineered tissues. This toolbox combines modular design and non-destructive fabricated design evaluation, evaluates biocompatibility and mechanical properties, and models angiogenesis.
Keywords:
3D printing; scaffolds; tissue engineering; vascularization.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Evaluation Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Biocompatible Materials / chemistry*
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Bone and Bones / blood supply
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Bone and Bones / physiology*
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Fumarates / chemistry
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Imaging, Three-Dimensional
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Materials Testing / methods*
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Models, Biological
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Neovascularization, Physiologic
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Platelet Endothelial Cell Adhesion Molecule-1 / metabolism
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Polypropylenes / chemistry
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Porosity
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Printing, Three-Dimensional*
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Rats, Sprague-Dawley
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Tissue Engineering / methods*
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Tissue Scaffolds / chemistry*
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X-Ray Microtomography
Substances
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Biocompatible Materials
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Fumarates
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Platelet Endothelial Cell Adhesion Molecule-1
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Polypropylenes
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poly(propylene fumarate)