Adherence to medical treatment in inflammatory bowel disease patients

Minerva Gastroenterol Dietol. 2014 Dec;60(4):269-74.

Abstract

Aim: Inflammatory bowel diseases (IBD) are a group of chronic intestinal conditions characterized by unpredictable course, with periods of flare-ups and remissions suggesting poor adherence to medical therapy. On the other hand adherence is one of the most common reason of failure in the treatment of chronic disease.

Methods: We have analyzed IBD patients' questionnaires, sent by IBD Society of Emilia-Romagna Region (Italy). The anonymous questionnaire included sex, age, qualification, management, disease duration, disease associated, previous surgery, use of homeopathy and self-medication and possible psychological support. We classified patients based on IBD type: Crohn's disease (CD) and ulcerative colitis (UC).

Results: A total of 559 IBD patients were analysed (50.1% female), 52.8% were affected by CD. Patients were followed by gastroenterologist in 84.7% of cases. 17.4% of patient reported non-adherence to medical therapy; univariate analysis showed that non-adherence was more frequent in young females followed-up by general practitioners, no difference was found in educational status or type of IBD. Factors independently associated with greater adherence to medical therapy were age (OR=2.039) and follow-up by gastroenterologist (OR=3.025).

Conclusion: Non-adherence should be taken into account in IBD patients and especially in young female. Gastroenterologists have a major role in promoting education.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Colitis, Ulcerative / drug therapy
  • Crohn Disease / drug therapy
  • Female
  • Health Surveys
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Inflammatory Bowel Diseases / diagnosis
  • Inflammatory Bowel Diseases / drug therapy*
  • Inflammatory Bowel Diseases / epidemiology
  • Italy / epidemiology
  • Male
  • Medication Adherence / statistics & numerical data*
  • Middle Aged
  • Risk Factors
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Immunosuppressive Agents