The tmRNA website

Corey M Hudson; Kelly P Williams

doi:10.1093/nar/gku1109

The tmRNA website

Nucleic Acids Res. 2015 Jan;43(Database issue):D138-40. doi: 10.1093/nar/gku1109. Epub 2014 Nov 5.

Authors

Corey M Hudson¹, Kelly P Williams²

Affiliations

¹ Sandia National Laboratories, Department of Systems Biology, Livermore, CA 94551, USA.
² Sandia National Laboratories, Department of Systems Biology, Livermore, CA 94551, USA kpwilli@sandia.gov.

Abstract

The transfer-messenger RNA (tmRNA) and its partner protein SmpB act together in resolving problems arising when translating bacterial ribosomes reach the end of mRNA with no stop codon. Their genes have been found in nearly all bacterial genomes and in some organelles. The tmRNA Website serves tmRNA sequences, alignments and feature annotations, and has recently moved to http://bioinformatics.sandia.gov/tmrna/. New features include software used to find the sequences, an update raising the number of unique tmRNA sequences from 492 to 1716, and a database of SmpB sequences which are served along with the tmRNA sequence from the same organism.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Databases, Nucleic Acid*
Genome, Bacterial
Internet
RNA, Bacterial / chemistry*
RNA, Bacterial / genetics
RNA-Binding Proteins / chemistry
RNA-Binding Proteins / genetics
Sequence Alignment
Sequence Analysis, RNA

Substances

RNA, Bacterial
RNA-Binding Proteins
small protein B
tmRNA