Sperm dynamics in tubular confinement

Veronika Magdanz; Britta Koch; Samuel Sanchez; Oliver G Schmidt

doi:10.1002/smll.201401881

Sperm dynamics in tubular confinement

Small. 2015 Feb 18;11(7):781-5. doi: 10.1002/smll.201401881. Epub 2014 Oct 30.

Authors

Veronika Magdanz¹, Britta Koch, Samuel Sanchez, Oliver G Schmidt

Affiliation

¹ Institute for Integrative Nanosciences, Leibniz Institute for Solid State and Materials Research, Helmholtzstr. 20, 01069, Dresden, Germany.

PMID: 25356740
DOI: 10.1002/smll.201401881

Abstract

An on-chip system that mimics tubular microenvironments is presented for the study of spermatozoa motion in confinement. Using rolled up transparent silicon oxide/dioxide microtubes, the influence of tube diameter on the velocity, directionality, and linearity of spermatozoa is investigated. Tubular microenvironments of diameters 20-45 μm facilitate sperm migration through channels.

Keywords: microchannels; microtubes; motile cells; spacial confinement; sperm migration.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cattle
Cellular Microenvironment*
Male
Silicon Dioxide / pharmacology
Sperm Motility / drug effects
Spermatozoa / cytology
Spermatozoa / drug effects
Spermatozoa / physiology*

Substances

Silicon Dioxide