Statin-induced insulin resistance through inflammasome activation: sailing between Scylla and Charybdis

Diabetes. 2014 Nov;63(11):3569-71. doi: 10.2337/db14-1059.

Authors

Patricia Mitchell¹, André Marette²

Affiliations

¹ Department of Medicine, Faculty of Medicine, Quebec Heart and Lung Institute, Laval University, Quebec, Quebec, Canada.
² Department of Medicine, Faculty of Medicine, Quebec Heart and Lung Institute, Laval University, Quebec, Quebec, Canada andre.marette@criucpq.ulaval.ca.

PMID: 25342725
DOI: 10.2337/db14-1059

No abstract available

Publication types

Comment

MeSH terms

Adipose Tissue / metabolism*
Animals
Carrier Proteins / metabolism*
Fatty Acids, Monounsaturated / therapeutic use*
Fluvastatin
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
Indoles / therapeutic use*
Inflammasomes / drug effects*
Inflammasomes / metabolism*
Male
NLR Family, Pyrin Domain-Containing 3 Protein

Substances

Carrier Proteins
Fatty Acids, Monounsaturated
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Indoles
Inflammasomes
NLR Family, Pyrin Domain-Containing 3 Protein
Nlrp3 protein, mouse
Fluvastatin