Antioxidant and immunoregulatory activity of polysaccharides from quinoa (Chenopodium quinoa Willd.)

Yang Yao; Zhenxing Shi; Guixing Ren

doi:10.3390/ijms151019307

Antioxidant and immunoregulatory activity of polysaccharides from quinoa (Chenopodium quinoa Willd.)

Int J Mol Sci. 2014 Oct 23;15(10):19307-18. doi: 10.3390/ijms151019307.

Authors

Yang Yao¹, Zhenxing Shi², Guixing Ren³

Affiliations

¹ Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China. yaoyang@caas.cn.
² Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China. shizhenxingmu@gmail.com.
³ Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing 100081, China. renguixing@caas.cn.

Abstract

The water-extractable (QWP) and the alkali-extractable (QAP) polysaccharides from quinoa (named QWP and QAP, respectively) and their four polysaccharide sub-fractions (QWP-1, QWP-2, QAP-1 and QAP-2), were isolated and purified by anion-exchange and gel filtration chromatography. QWP-1 and QWP-2 were composed of Rha, Ara, Gal and GalA. QAP-1 and QAP-2 were composed of Rha, Ara, Man, Gal and GalA. Antioxidant and immunoregulatory activities of the polysaccharides were evaluated. The results showed that QWP-1, QWP-2, QAP-1 and QAP-2 had significant antioxidant and immunoregulatory activities. The results suggest that QWP-1, QWP-2, QAP-1 and QAP-2 could be used as potential antioxidants and immunomodulators.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antioxidants / chemistry*
Chenopodium quinoa / chemistry*
Immunologic Factors / chemistry*
Plant Extracts / chemistry*
Polysaccharides / chemistry*

Substances

Antioxidants
Immunologic Factors
Plant Extracts
Polysaccharides