Chronic disabling disease--impact on outcomes and costs in emergency medical admissions

QJM. 2015 May;108(5):387-96. doi: 10.1093/qjmed/hcu217. Epub 2014 Oct 21.

Abstract

Background: Chronic disabling disease is present in nearly 90% of emergency medical admissions. We have examined its impact on outcomes and costs in one institution, using a database of episodes collected prospectively over 12 years.

Methods: All emergency admissions (66,933 episodes; 36,271 patients) to St James' Hospital over a 12-year period (2002-13) were evaluated in relation to 30-day in-hospital mortality, length of stay (LOS) and hospital costs. Predictor variables (identified univariately) were entered into a multi-variable logistic regression model to predict 30-day in-hospital mortality. The data were also modelled as count data (absolute LOS, total cost) using zero-truncated Poisson regression.

Results: Acute illness severity was the best independent predictor of mortality; chronic disabling disease was an independent predictor (P < 0.001) for patients with 4+ disabling conditions. Age, adjusted for other predictors, was only independently predictive of mortality for patient 85+ years. Chronic disabling disease was an independent predictor of LOS increasing linearly with incidence rate ratios of 1.35 (95% CI: 1.29, 1.42), 1.59 (95% CI: 1.51, 1.66), 1.73 (95% CI: 1.65, 1.83) and 1.74 (95% CI: 1.65, 1.84) for those with 1, 2, 3 or 4+ disabling conditions, respectively. Age, as a predictor of LOS was strongly correlated with the presence of disabling disease. Chronic disabling disease independently predicted costs non-linearly; those with 2 or more disabling conditions had particularly high total hospital costs.

Conclusion: Chronic disabling disease is an independent predictor of hospital LOS and costs in unselected emergency admissions; adjusted for illness severity, it is only a mortality predictor for those with multiple disabling conditions.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Chronic Disease*
  • Databases, Factual
  • Emergency Medicine
  • Emergency Service, Hospital / economics*
  • Female
  • Health Care Costs*
  • Hospital Mortality*
  • Humans
  • Length of Stay / statistics & numerical data*
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Patient Admission / economics*
  • Prognosis
  • Severity of Illness Index