Diagnostic and therapeutic quandaries in a patient with primary hepatic lymphoma and concurrent hepatitis C infection

Muhajir Mohamed; Ruchira Fernando

doi:10.1007/s12288-014-0431-z

Diagnostic and therapeutic quandaries in a patient with primary hepatic lymphoma and concurrent hepatitis C infection

Indian J Hematol Blood Transfus. 2014 Sep;30(Suppl 1):394-7. doi: 10.1007/s12288-014-0431-z. Epub 2014 Jul 16.

Authors

Muhajir Mohamed¹, Ruchira Fernando²

Affiliations

¹ Haematology Department, Launceston General Hospital, Launceston, TAS Australia ; Launceston Clinical School, University of Tasmania, Launceston, TAS Australia.
² Pathology Department, Launceston General Hospital, Launceston, TAS Australia.

Abstract

Primary hepatic lymphoma (PHL) is a very rare sub-type of non-Hodgkin's lymphoma and hepatitis C infection may be a contributory factor. The association of hepatitis C infection and PHL causes difficulties in management since safety of rituximab in such situations is unclear due to lack of evidence. The role of anti-viral therapy in combination with chemotherapy is also uncertain. We describe the diagnostic and therapeutic challenges posed by a patient who was diagnosed with PHL and concurrent hepatitis C infection.

Keywords: Hepatitis C; Primary hepatic lymphoma.

Publication types

Case Reports