Correlation between corneal thickness and optic disc morphology in normal tension glaucoma using modern technical analysis

Rom J Morphol Embryol. 2014;55(3):857-62.

Abstract

The purpose of this study was to evaluate the relationship between central corneal thickness (CCT) and optic disc morphology in normal tension glaucoma (NTG). Patients with NTG underwent eye examination, optic disc imaging with Heildelberg Retina Tomograph II (HRT II) and ultrasound corneal pachymetry. The morphological parameters of the optic discs were used to classify the eyes into four groups: generalized enlargement (GE) type, myopic glaucomatous (MY) type, focal ischemic (FI) type and senile sclerotic (SS) type. A correlation between CCT and optic disc morphology obtained by HRT II was calculated. Multiple comparison and post hoc tests were performed in order to determine the significance of the differences between the four groups. The strongest correlation was between CCT and the parameters of optic disc imaging obtained at HRT II in the GE type of optic disc.

MeSH terms

  • Corneal Pachymetry / methods*
  • Humans
  • Low Tension Glaucoma / diagnosis*
  • Low Tension Glaucoma / pathology*
  • Optic Disk / pathology*
  • Optic Nerve / pathology
  • Retina / pathology
  • Tomography / methods*