A rare complication of gastric bypass (weight loss) surgery: nesidioblastosis

Int J Surg Pathol. 2015 Feb;23(1):68-70. doi: 10.1177/1066896914554833. Epub 2014 Oct 16.

Abstract

Here, we present the case of a 31-year-old woman patient who underwent distal pancreatectomy with the history of gastric bypass surgery for obesity. The final histopathological diagnosis of the lesion was nesidioblastosis. Nesidioblastosis is the most common cause of organic persistent hyperinsulinemic hypoglycemia in newborns; however, it is rare in adults. In adults, it is difficult to diagnose nesidioblastosis with only clinical findings. The definitive diagnosis of the disease depends on the histopathological examination of pancreatic tissue and the exclusion of insulinoma.

Keywords: gastric bypass; hyperinsulinemic hypoglycemia; nesidioblastosis; weight loss.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Gastric Bypass / adverse effects*
  • Humans
  • Nesidioblastosis / etiology*
  • Nesidioblastosis / pathology
  • Nesidioblastosis / surgery
  • Obesity / surgery*
  • Pancreatectomy*
  • Treatment Outcome