Diffusion-weighted intensity magnetic resonance in the preoperative diagnosis of cholesteatoma

ORL J Otorhinolaryngol Relat Spec. 2014;76(4):212-21. doi: 10.1159/000365931. Epub 2014 Oct 14.

Abstract

We have analyzed the preoperative diagnosis of cholesteatoma through the use of diffusion-weighted intensity magnetic resonance (DWI-MR) in 16 consecutive patients suffering from chronic otitis media with clinical and radiological (by computed tomography) suspicion of cholesteatoma. In particular, we compared the radiological data with intraoperative ones, verifying the correspondence (in terms of sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy) between what is reported by DWI-MR and what is actually detectable at the time of surgery. Furthermore, we identified the most reliable DWI-MR sequence [single-shot (SSh) echo planar imaging (EPI) vs. multi-shot turbo spin-echo not-EPI] to detect cholesteatoma and reduce the time for examination. The obtained data on computed tomography scans revealed low diagnostic accuracy (56%); DWI-MR, instead, showed higher values, especially using not-EPI sequences (93.75 vs. 68.75% obtained by SSh-EPI sequences).

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Cholesteatoma, Middle Ear / diagnosis*
  • Cholesteatoma, Middle Ear / surgery
  • Echo-Planar Imaging / methods*
  • False Negative Reactions
  • Female
  • Humans
  • Magnetic Resonance Spectroscopy / methods*
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Preoperative Period
  • Prospective Studies
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed
  • Young Adult