[Surgical treatment of type 2 diabetes mellitus]

Cir Cir. 2014 Mar-Apr;82(2):219-30.
[Article in Spanish]

Abstract

Sustained remission of type 2 diabetes mellitus and significantly improved hyperlipidemia and arterial hypertension, control has been achieves in both lean and obese patient after bariatric surgery procedures or other gastrointestinal surgical procedures. It has been demonstrated that the metabolic effects of bariatric surgery in these patients derives not only in reducing weight and caloric intake, but also endocrine changes resulting from surgical manifestation gastrointestinal tract. In this article we review the clinical outcomes of such interventions (collectively called "metabolic surgery") and the perspectives on the role that these surgeries play in the treatment of patients with type 2 diabetes mellitus.

Diversos procedimientos de cirugía bariátrica y otros quirúrgicos gastrointestinales pueden remitir la diabetes mellitus tipo 2 y disminuir la hiperlipidemia e hipertensión arterial en pacientes obesos y no obesos. Está demostrado que en esos pacientes los efectos metabólicos de la cirugía bariátrica no sólo se reflejan en pérdida de peso e ingesta calórica, sino también en cambios endocrinos resultantes de la manifestación quirúrgica del tubo gastrointestinal. Se revisan los resultados clínicos de esas intervenciones ("cirugía metabólica") en pacientes con diabetes mellitus tipo 2 y las perspectivas de su papel en el tratamiento de la diabetes mellitus tipo 2.

Keywords: Bariatric surgery; cirugía bariátrica; cirugía metabólica; diabetes mellitus tipo 2; metabolic surgery.

Publication types

  • Review

MeSH terms

  • Bariatric Surgery*
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetes Mellitus, Type 2 / surgery*
  • Energy Intake
  • Gastrectomy
  • Ghrelin / metabolism
  • Humans
  • Hyperlipidemias / complications
  • Hypertension / complications
  • Incretins / metabolism
  • Insulin Resistance
  • Intestine, Small / metabolism
  • Intestine, Small / physiopathology
  • Peptide YY / metabolism
  • Postgastrectomy Syndromes / physiopathology
  • Weight Loss

Substances

  • Ghrelin
  • Incretins
  • Peptide YY