Abstract
We developed a ratiometric fluorescent probe for sensing HOCl based on coumarin and rhodamine acid that is directly used as a detection moiety. The probe shows high selectivity and sensitivity toward HOCl under best working conditions of myeloperoxidase by which HOCl can be generated from hydrogen peroxide and chloride.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Cell Line
-
Coumarins / chemistry*
-
Fluorescent Dyes / chemistry*
-
Hypochlorous Acid / analysis*
-
Mice
-
Molecular Structure
-
Rhodamines / chemistry*
-
Spectrometry, Fluorescence
Substances
-
Coumarins
-
Fluorescent Dyes
-
Rhodamines
-
Hypochlorous Acid
-
coumarin