Clinical and forensic signs related to chemical burns: a mechanistic approach

Burns. 2015 Jun;41(4):658-79. doi: 10.1016/j.burns.2014.09.002. Epub 2014 Oct 1.

Abstract

This manuscript highlights and critically analyses clinical and forensic signs related to chemical burns. Signs that may lead to suspicion of a particular chemical are thoroughly discussed regarding its underlying mechanisms. Burns due to sulfuric, hydrofluoric, nitric, hydrochloric (muriatic) and acetic (including derivatives) acids, hydrogen sulphide, sodium (caustic soda) and calcium (cement) hydroxides, paraquat, burns after inflation and rupture of airbags, povidone-iodine, chlorhexidine/alcohol (in preterm infants), laxatives, and vesicants (warfare agents), will be reviewed since these are the most common agents found in daily practice, for which relevant and timed information may be helpful in formulating an emergency treatment protocols and toxicological analysis.

Keywords: Acetic acid and derivatives; Calcium hydroxide (cement); Chemical burns; Chlorhexidine/alcohol; Hydrochloric acid (muriatic acid); Hydrofluoric acid; Hydrogen sulphide; Inflation and rupture of airbags; Laxatives; Nitric acid; Paraquat; Povidone–iodine; Sodium hydoxide (caustic soda); Sulfuric acid; Vesicants.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acetic Acid / adverse effects
  • Acids / adverse effects*
  • Air Bags / adverse effects
  • Air Pollutants / adverse effects
  • Anti-Infective Agents, Local / adverse effects*
  • Bone Cements / adverse effects
  • Burns, Chemical / etiology
  • Burns, Chemical / pathology*
  • Calcium Hydroxide / adverse effects
  • Caustics / adverse effects*
  • Chemical Warfare Agents / adverse effects*
  • Chlorhexidine / adverse effects
  • Explosive Agents / adverse effects
  • Forensic Medicine*
  • Herbicides / adverse effects
  • Humans
  • Hydrochloric Acid / adverse effects
  • Hydrogen Sulfide / adverse effects
  • Irritants / adverse effects*
  • Laxatives / adverse effects
  • Nitric Acid / adverse effects
  • Paraquat / adverse effects
  • Povidone-Iodine / adverse effects
  • Sodium Hydroxide / adverse effects

Substances

  • Acids
  • Air Pollutants
  • Anti-Infective Agents, Local
  • Bone Cements
  • Caustics
  • Chemical Warfare Agents
  • Explosive Agents
  • Herbicides
  • Irritants
  • Laxatives
  • Nitric Acid
  • Sodium Hydroxide
  • Povidone-Iodine
  • Calcium Hydroxide
  • Paraquat
  • Acetic Acid
  • Hydrochloric Acid
  • Chlorhexidine
  • Hydrogen Sulfide