Chronic hepatitis E virus infection in a pediatric female liver transplant recipient

Ana Maria Passos-Castilho; Gilda Porta; Irene K Miura; Renata P S Pugliese; Vera L B Danesi; Adriana Porta; Teresa Guimarães; João Seda; Eduardo Antunes; Celso F H Granato

doi:10.1128/JCM.02286-14

Chronic hepatitis E virus infection in a pediatric female liver transplant recipient

J Clin Microbiol. 2014 Dec;52(12):4425-7. doi: 10.1128/JCM.02286-14. Epub 2014 Oct 1.

Affiliations

¹ Division of Infectious Diseases, Department of Medicine, Federal University of Sao Paulo, Sao Paulo, SP, Brazil anampassos@gmail.com.
² A.C. Camargo Cancer Center, Sao Paulo, SP, Brazil.
³ Division of Infectious Diseases, Department of Medicine, Federal University of Sao Paulo, Sao Paulo, SP, Brazil Fleury SA Group, Sao Paulo, SP, Brazil.

Abstract

We describe a case of chronic hepatitis E virus (HEV) infection in a 13-year-old female liver transplant recipient with recurrent increased aminotransferase levels and acute cellular rejection. This finding demonstrates that chronic HEV infection can occur and should be further investigated in immunocompromised patients in Latin America.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Child, Preschool
Female
Graft Rejection
Hepatitis E virus / isolation & purification*
Hepatitis, Chronic / diagnosis*
Hepatitis, Chronic / virology
Humans
Immunocompromised Host
Latin America
Liver Transplantation*
Molecular Sequence Data
RNA, Viral / genetics
Sequence Analysis, DNA
Transaminases / blood
Transplant Recipients*

Substances

RNA, Viral
Transaminases

Associated data

GENBANK/KF152884
GENBANK/KM502569