Catalytic methylation of aromatic amines with formic acid as the unique carbon and hydrogen source

Chem Commun (Camb). 2014 Nov 21;50(90):14033-6. doi: 10.1039/c4cc05908e.

Abstract

A novel methodology is presented for the direct methylation of amines, using formic acid as a unique source of carbon and hydrogen. Based on ruthenium(II) catalysts, the formation of the N-CH3 group proceeds via an efficient formylation/transfer hydrogenation pathway.