Testicular myeloid sarcoma: a rare manifestation of acute myeloid leukemia in an infant

Christine N Tran; Angela M B Collie; Aron Flagg; Audrey Rhee

doi:10.1016/j.urology.2014.07.005

Testicular myeloid sarcoma: a rare manifestation of acute myeloid leukemia in an infant

Urology. 2014 Oct;84(4):925-7. doi: 10.1016/j.urology.2014.07.005.

Authors

Christine N Tran¹, Angela M B Collie², Aron Flagg³, Audrey Rhee⁴

Affiliations

¹ Department of Urology, The Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH. Electronic address: tranc@ccf.org.
² Department of Clinical Pathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, OH.
³ Department of Pediatric Hematology and Oncology, Cleveland Clinic Foundation, Cleveland, OH.
⁴ Department of Urology, The Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH.

PMID: 25260454
DOI: 10.1016/j.urology.2014.07.005

Abstract

Myeloid sarcoma manifesting in the testis is rare and may occur concomitantly with bone marrow disease or as a separate entity. We describe our experience with a 6-month-old boy who presented with painless scrotal swelling and was found to have bilateral testicular masses on ultrasonography. The patient underwent unilateral radical inguinal orchiectomy. Surgical pathology revealed myeloid sarcoma of the testicle. He developed peripheral blood involvement 1 week postoperatively. Bone marrow biopsy showed acute myeloid leukemia. He is in remission after 2 cycles of induction chemotherapy, local radiation therapy, and allogeneic bone marrow transplantation.

Publication types

Case Reports

MeSH terms

Humans
Infant
Leukemia, Myeloid, Acute / complications*
Leukemia, Myeloid, Acute / diagnosis
Male
Sarcoma, Myeloid / etiology*
Testicular Neoplasms / etiology*