[Successful treatment of metastatic testicular tumor of extreme size]

Magy Onkol. 2014 Sep;58(3):225-8. Epub 2014 Aug 2.
[Article in Hungarian]

Abstract

Testicular cancer is the most common cancer in young males. Testicular cancer has one of the highest cure rates of all cancers: with modern chemotherapy treatment five-year survival rate exceeds 90 percent overall, and reaches almost 100 percent in early stages. However, these favorable results can only be achieved if these patients are transferred to a reference center, because better outcome was reported for patients who had been treated in a high volume center. Strict adherence to therapeutic protocol is vital for good results. We present a case of a testicular cancer patient with very advanced disease and poor performance status, who was deemed incurable by another oncological center. We achieved complete remission by strictly adhering to the protocol, and using all the available supportive measures. We would like to demonstrate the difficulties we were facing while treating this poor prognostic patient.

A fiatal férfiak leggyakoribb szolid tumora a hererák. A kemoterápiás kezelés elõrehaladott esetekben is igen jelentõs javulást eredményez, a teljes gyógyulás elérheti akár a 95%-ot is. Ezt a kedvezõ gyógyulási arányt azonban csak a nagy tapasztalattal bíró centrumok tudják elérni, ezért világszerte az a törekvés, hogy a heredaganatos betegeket kiemelt centrumokban kezeljék. A gyógyulás legfontosabb prediktív faktora a terápiás protokoll szigorú betartása. Esetbemutatásunkban onkológiailag kezelhetetlennek tartott betegnél, szakmai revíziót követõen, az aktuális protokoll betartásával értünk el gyógyulást. Esetünkkel szeretnénk rávilágítani arra, hogy a heredaganatos betegek kezelése kapcsán milyen szakmai nehézségek merülhetnek fel.

Publication types

  • English Abstract

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bleomycin / administration & dosage
  • Bleomycin / adverse effects
  • Cisplatin / administration & dosage
  • Cisplatin / adverse effects
  • Depression / etiology
  • Disease Progression
  • Drug Administration Schedule
  • Etoposide / administration & dosage
  • Etoposide / adverse effects
  • Febrile Neutropenia / chemically induced
  • Humans
  • Interdisciplinary Communication
  • Male
  • Middle Aged
  • Orchiectomy*
  • Patient Care Team
  • Prognosis
  • Quality of Life
  • Remission Induction / methods
  • Status Epilepticus / chemically induced
  • Testicular Neoplasms / drug therapy*
  • Testicular Neoplasms / pathology*
  • Testicular Neoplasms / psychology
  • Testicular Neoplasms / surgery
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Venous Thrombosis / chemically induced

Substances

  • Bleomycin
  • Etoposide
  • Cisplatin

Supplementary concepts

  • BEP protocol