Manganese Encephalopathy among Ephedron Abusers

J Neuroimaging. 2015 Sep-Oct;25(5):832-5. doi: 10.1111/jon.12173. Epub 2014 Sep 26.

Abstract

Ephedrone encephalopathy is referred to as a group of symptoms of manganese deposition within the central nervous system (CNS), resulting from the abuse of ephedrone (methcathinone), obtained in reaction using the excess amount of manganese-containing oxidants. The diagnosis is based on the contrast-enhanced head MRI findings characteristic for this syndrome, clinical manifestation and history of ephedrone use. The syndrome has been reported in recent years in young people from Eastern Europe and Russia with a history of ephedrone overuse. However, no report has ever been published on ephedrone encephalopathy in Polish patients.

Keywords: HIV infection; Manganese-induced Parkinsonism; Poland.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / chemically induced*
  • Humans
  • Male
  • Manganese Poisoning / etiology*
  • Manganese Poisoning / pathology*
  • Propiophenones / poisoning*
  • Substance-Related Disorders / etiology*
  • Substance-Related Disorders / pathology*
  • Young Adult

Substances

  • Propiophenones
  • monomethylpropion