Impact of a Fast-track Esophagectomy Protocol on Esophageal Cancer Patient Outcomes and Hospital Charges

Ann Surg. 2015 Jun;261(6):1114-23. doi: 10.1097/SLA.0000000000000971.

Abstract

Objective: To evaluate the effects of a fast-track esophagectomy protocol (FTEP) on esophageal cancer patients' safety, length of hospital stay (LOS), and hospital charges.

Background: FTEP involved transferring patients to the telemetry unit instead of the surgical intensive care unit (SICU) after esophagectomy.

Methods: We retrospectively reviewed 708 consecutive patients who underwent esophagectomy for primary esophageal cancer during the 4 years before (group A; 322 patients) or 4 years after (group B; 386 patients) the institution of an FTEP. Postoperative morbidity and mortality, LOS, and hospital charges were reviewed.

Results: Compared with group A, group B had significantly shorter median LOS (12 days vs 8 days; P < 0.001); lower mean numbers of SICU days (4.5 days vs 1.2 days; P < 0.001) and telemetry days (12.7 days vs 9.7 days; P < 0.001); and lower rates of atrial arrhythmia (27% vs 19%; P = 0.013) and pulmonary complications (27% vs 20%; P = 0.016). Multivariable analysis revealed FTEP to be associated with shorter LOS (P < 0.001) even after adjustment for predictors like tumor histology and location. FTEP was also associated with a lower rate of pulmonary complications (odds ratio = 0.655; 95% confidence interval = 0.456, 0.942; P = 0.022). In addition, the median hospital charges associated with primary admission and readmission within 90 days for group B ($65,649) were lower than that for group A ($79,117; P < 0.001).

Conclusions: These findings suggest that an FTEP reduces patients' LOS, perioperative morbidity, and hospital charges.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / surgery*
  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / surgery*
  • Clinical Protocols
  • Esophageal Neoplasms / surgery*
  • Esophagectomy* / economics
  • Esophagectomy* / mortality
  • Esophagectomy* / statistics & numerical data
  • Female
  • Hospital Charges*
  • Humans
  • Intensive Care Units
  • Length of Stay
  • Male
  • Middle Aged
  • Morbidity
  • Patient Safety / economics
  • Patient Safety / standards
  • Postoperative Care / economics
  • Postoperative Care / methods*
  • Retrospective Studies
  • Telemetry
  • Treatment Outcome
  • Young Adult