Abstract
A novel and efficient cascade annulation of tertiary α-hydroxy ketones and dimethyl but-2-ynedioate is reported. The reaction, which only requires a base as the promoter, provides a straightforward access to polysubstituted pyrano[4,3-a]quinolizine-1,4,6(2H)-triones and 2H-pyran-2,5(6H)-diones under very mild reaction conditions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / chemical synthesis*
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Alkynes / chemistry
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Crystallography, X-Ray
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Dicarboxylic Acids / chemistry*
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Ketones / chemistry*
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Models, Molecular
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Molecular Structure
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Pyrones / chemical synthesis*
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Pyrones / chemistry
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Quinolizines / chemistry*
Substances
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Alkynes
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Dicarboxylic Acids
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Ketones
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Pyrones
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Quinolizines