The International Classification of Functioning Disability and Health (ICF) represents a general framework for concepts of health and disability. The number of patients undergoing Total knee arthroplasty (TKA) is increasing worldwide. Capturing the different health-related ICF domains in this increasing number of patients with TKA requires clinicians and researchers to be familiar with the tools that can be used in daily clinical practice to capture these health-related domains. This paper aimed to review the outcome measures related to the different ICF domains in patients with TKA and to review the psychometric properties of these outcome measures. An electronic search for relevant articles using MEDLINE and CINHAL databases up to March 2014 was performed. In addition to the electronic search, the articles retrieved were searched manually for relevant studies. Impairment-based outcome measures important to patients with TKA included measures of knee pain intensity, knee joint mobility, and muscle performance. Outcome measures capturing activity limitation in patients with TKA included both self-reported and performance-based measures as each capture a different aspect of the activity limitation construct. The disability component of the late life function and disability instrument can be used to quantify participation restriction patients with TKA. Clinicians and researchers are encouraged to measure the different health-related domains in patients with TKA using the outcome measures presented in this review.