Efficacy and safety of plasma exchange: ann 11-year single-center experience of 2730 procedures in 317 patients

Joan Cid; Gloria Carbassé; Bienvenida Andreu; Antonio Baltanás; Ana Garcia-Carulla; Miguel Lozano

doi:10.1016/j.transci.2014.08.018

Efficacy and safety of plasma exchange: ann 11-year single-center experience of 2730 procedures in 317 patients

Transfus Apher Sci. 2014 Oct;51(2):209-14. doi: 10.1016/j.transci.2014.08.018. Epub 2014 Aug 27.

Authors

Joan Cid¹, Gloria Carbassé², Bienvenida Andreu², Antonio Baltanás², Ana Garcia-Carulla², Miguel Lozano²

Affiliations

¹ Apheresis Unit, Department of Hemotherapy and Hemostasis, CDB, IDIBAPS, Hospital Clínic, University of Barcelona, Barcelona, Spain. Electronic address: jcid@clinic.ub.es.
² Apheresis Unit, Department of Hemotherapy and Hemostasis, CDB, IDIBAPS, Hospital Clínic, University of Barcelona, Barcelona, Spain.

PMID: 25217991
DOI: 10.1016/j.transci.2014.08.018

Abstract

We reviewed retrospectively 317 patients who received 2730 plasma exchange (PE) procedures. According to guidelines published by the American Society for Apheresis (ASFA) in 2013, there were 220 (69%), 55 (17%), 32 (9%), and 7 (4%) patients who were treated with PE for a disease or condition considered as category I, II, III, and IV, respectively. Overall, 73%, 72%, and 69% of the patients showed an improvement of the underlying disease or condition at the end of the PE, and at 3 months and at 6 months after finishing the PE, respectively. We observed adverse effects in 90 (3%) PEs.

Keywords: Efficacy; Plasma exchange; Safety.

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Female
Humans
Male
Middle Aged
Plasma Exchange / adverse effects
Plasma Exchange / methods*
Practice Guidelines as Topic
Retrospective Studies
Safety*