The solubility of disodium 5'-guanylate heptahydrate (5'-GMPNa2) in binary aqueous methanol solvent mixtures with the temperature ranging from 278.15 to 323.15K was measured by a dynamic method with a laser monitoring observation technique. The solubility data were correlated with the Combined Nearly Ideal Binary Solvent/Redlich-Kister (CNIBS/R-K) model and the modified Jouyban-Acree model, respectively. For the ten groups of data studied, the CNIBS/R-K model was found to provide a more accurate mathematical representation of the experimental data, while the modified Jouyban-Acree model containing provisions for correlating both the solvent composition and temperature.
Keywords: Correlation; Disodium 5′-guanylate heptahydrate; Measurement; Solubility.
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