Abstract
Initially described as an RNA surveillance pathway, nonsense-mediated decay (NMD) is also recognized to function in the regulation of host gene expression. In this issue of Cell Host & Microbe, three studies describe NMD-mediated defense strategies of plants and mammalian cells in response to pathogen infection.
Copyright © 2014 Elsevier Inc. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
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Comment
MeSH terms
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Alphavirus Infections / virology*
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Arabidopsis / genetics*
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Arabidopsis / immunology*
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Carrier Proteins / metabolism*
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Humans
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Nonsense Mediated mRNA Decay*
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Plant Diseases / virology*
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Potexvirus / genetics*
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Pseudomonas syringae / physiology*
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RNA Helicases
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RNA, Viral / genetics*
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Receptors, Immunologic / genetics*
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Receptors, Immunologic / immunology*
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Semliki forest virus / physiology*
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Trans-Activators / metabolism*
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Virus Replication*
Substances
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Carrier Proteins
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RNA, Viral
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Receptors, Immunologic
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SMG5 protein, human
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SMG7 protein, human
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Trans-Activators
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RNA Helicases
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UPF1 protein, human