Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels-Alder reaction

Jonathan C Moore; E Stephen Davies; Darren A Walsh; Pallavi Sharma; John E Moses

doi:10.1039/c4cc05906a

Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels-Alder reaction

Chem Commun (Camb). 2014 Oct 25;50(83):12523-5. doi: 10.1039/c4cc05906a.

Authors

Jonathan C Moore¹, E Stephen Davies, Darren A Walsh, Pallavi Sharma, John E Moses

Affiliation

¹ School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 1RD, UK. john.moses@nottingham.ac.uk.

PMID: 25196219
DOI: 10.1039/c4cc05906a

Abstract

The application of electrochemical reactions in natural product synthesis has burgeoned in recent years. We herein report a formal synthesis of the complex and dimeric natural product kingianin A, which employs an electrochemically-mediated radical cation Diels-Alder cycloaddition as the key step.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biological Products / chemical synthesis*
Cycloaddition Reaction / methods*
Electrochemical Techniques / methods*
Lauraceae / chemistry*
Polycyclic Aromatic Hydrocarbons / chemical synthesis*

Substances

Biological Products
Polycyclic Aromatic Hydrocarbons
kingianin A