Allele frequencies for 15 autosomal STR loci and haplotype data for 17 Y-STR loci in a population from Belize

Shahida Flores; Jie Sun; Jonathan King; Arthur Eisenberg; Bruce Budowle

doi:10.1007/s00414-014-1082-1

Allele frequencies for 15 autosomal STR loci and haplotype data for 17 Y-STR loci in a population from Belize

Int J Legal Med. 2015 Nov;129(6):1217-8. doi: 10.1007/s00414-014-1082-1. Epub 2014 Sep 6.

Authors

Shahida Flores¹, Jie Sun², Jonathan King², Arthur Eisenberg², Bruce Budowle^{2

3}

Affiliations

¹ Institute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX, 76107, USA. floressk@livemail.uthscsa.edu.
² Institute of Applied Genetics, Department of Molecular and Medical Genetics, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX, 76107, USA.
³ Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia.

PMID: 25193820
DOI: 10.1007/s00414-014-1082-1

Abstract

Allele frequencies for 15 autosomal STR loci (N = 290) and haplotype data for 17 Y-STR loci (N = 157) were determined for an admixed population from Belize. There were no detectable departures from Hardy-Weinberg equilibrium expectations at any autosomal STR loci except for the D8S1179 locus (p = 0.002). The combined power of discrimination (PD) and combined power of exclusion (PE) were greater than 0.99999999 and 0.99999951, respectively. In addition, a total of 144 distinct Y-STR haplotypes were observed with 133 Y-STR haplotypes observed only once. The most common Y-STR haplotype was observed three times for two separate haplotypes. The various analyses of these forensically relevant STR loci showed that these markers are informative in the Belize population for forensic and parentage testing applications.

Keywords: Autosomal STR; Belize; DNA typing; Y-STR.

MeSH terms

Belize
Chromosomes, Human, Y*
DNA Fingerprinting*
Female
Gene Frequency*
Genetics, Population*
Haplotypes
Humans
Male
Microsatellite Repeats*
Polymerase Chain Reaction