Lighting Up pre-mRNA recognition

Mol Cell. 2014 Sep 4;55(5):649-51. doi: 10.1016/j.molcel.2014.08.021.

Abstract

Systematic analyses, by UV crosslinking, of the precise binding sites for 23 different proteins across the yeast pre-mRNA population have given insights into the in vivo assembly of, and interactions between, pre-mRNA processing, packaging, and transport complexes.

Publication types

  • Comment

MeSH terms

  • Acetaldehyde / metabolism*
  • Aldehyde Dehydrogenase / genetics*
  • Aldehyde Dehydrogenase / metabolism*
  • Animals
  • Embryo, Mammalian / metabolism*
  • Ethanol / toxicity*
  • Fanconi Anemia / pathology*
  • Fanconi Anemia Complementation Group A Protein / genetics*
  • Female
  • Humans
  • Pregnancy

Substances

  • Fanconi Anemia Complementation Group A Protein
  • Ethanol
  • Aldehyde Dehydrogenase
  • Acetaldehyde