Epstein-Barr virus-specific adoptive immunotherapy: a new horizon for multiple sclerosis treatment?

Immunotherapy. 2014;6(6):659-61. doi: 10.2217/imt.14.43.
No abstract available

Keywords: B cell; CD8 T cell; Epstein–Barr virus; adoptive immunotherapy; multiple sclerosis; treatment.

Publication types

  • Case Reports
  • Editorial

MeSH terms

  • Adenoviridae / genetics
  • Adoptive Transfer / methods*
  • Adult
  • Antigens, Viral / genetics
  • Antigens, Viral / immunology
  • B-Lymphocytes / immunology
  • CD8-Positive T-Lymphocytes / immunology
  • CD8-Positive T-Lymphocytes / metabolism
  • CD8-Positive T-Lymphocytes / transplantation*
  • Cell Differentiation / immunology
  • Cell Proliferation
  • Epitopes, T-Lymphocyte / genetics
  • Epitopes, T-Lymphocyte / immunology
  • Epstein-Barr Virus Nuclear Antigens / genetics
  • Epstein-Barr Virus Nuclear Antigens / immunology
  • Genetic Vectors / administration & dosage
  • Genetic Vectors / genetics
  • Genetic Vectors / immunology
  • Herpesvirus 4, Human / genetics
  • Herpesvirus 4, Human / immunology*
  • Humans
  • Immunotherapy / methods*
  • Male
  • Multiple Sclerosis / immunology
  • Multiple Sclerosis / therapy*
  • Treatment Outcome
  • Viral Matrix Proteins / genetics
  • Viral Matrix Proteins / immunology
  • Viral Proteins / genetics
  • Viral Proteins / immunology*

Substances

  • Antigens, Viral
  • EBV-associated membrane antigen, Epstein-Barr virus
  • Epitopes, T-Lymphocyte
  • Epstein-Barr Virus Nuclear Antigens
  • Viral Matrix Proteins
  • Viral Proteins
  • EBV-encoded nuclear antigen 1