Radiogenomic imaging-linking diagnostic imaging and molecular diagnostics

World J Radiol. 2014 Aug 28;6(8):519-22. doi: 10.4329/wjr.v6.i8.519.

Abstract

Radiogenomic imaging refers to the correlation between cancer imaging features and gene expression and is one of the most promising areas within science and medicine. High-throughput biological techniques have reshaped the perspective of biomedical research allowing for fast and efficient assessment of the entire molecular topography of a cell's physiology providing new insights into human cancers. The use of non-invasive imaging tools for gene expression profiling of solid tumors could serve as a means for linking specific imaging features with specific gene expression patterns thereby allowing for more accurate diagnosis and prognosis and obviating the need for high-risk invasive biopsy procedures. This review focuses on the medical imaging part as one of the main drivers for the development of radiogenomic imaging.

Keywords: Diagnostic imaging; Personalized medicine; Radiogenomic imaging.

Publication types

  • Review