Molecular characterization of an infectious bronchitis virus strain isolated from northern China in 2012

Arch Virol. 2014 Dec;159(12):3457-61. doi: 10.1007/s00705-014-2213-1. Epub 2014 Aug 29.

Abstract

This study reports the complete genome sequence of an infectious bronchitis virus (CK/CH/SD/121220, KJ128295) isolated in 2012 from Shandong Province in northern China. The genome is 27,666 nt long, comprising six genes and 5' and 3' untranslated regions. The full-length genome of the CK/CH/SD/121220 isolate had the highest nucleotide sequence identity (96.7 %) to the YX10 strain. Sites of recombination were identified in the genes 1ab, S, 5a, 5b and N, with their putative parental strains belonging to the QX- and YN-type subgroups, which are already circulating in China. Our findings suggest an important role played by recombination in IBV evolution.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3' Untranslated Regions
  • 5' Untranslated Regions
  • China
  • Cluster Analysis
  • Genes, Viral
  • Genome, Viral*
  • Infectious bronchitis virus / genetics*
  • Infectious bronchitis virus / isolation & purification
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Viral / genetics*
  • Recombination, Genetic
  • Sequence Analysis, DNA*
  • Sequence Homology, Nucleic Acid

Substances

  • 3' Untranslated Regions
  • 5' Untranslated Regions
  • RNA, Viral

Associated data

  • GENBANK/KJ128295