[Pulsed-dose rate brachytherapy in cervical cancers: why, how?]

Cancer Radiother. 2014 Oct;18(5-6):447-51. doi: 10.1016/j.canrad.2014.06.010. Epub 2014 Aug 22.
[Article in French]

Abstract

The end of the production of 192 iridium wires terminates low dose rate brachytherapy and requires to move towards pulsed-dose rate or high-dose rate brachytherapy. In the case of gynecological cancers, technical alternatives exist, and many teams have already taken the step of pulsed-dose rate for scientific reasons. Using a projector source is indeed a prerequisite for 3D brachytherapy, which gradually installs as a standard treatment in the treatment of cervical cancers. For other centers, this change implies beyond investments in equipment and training, organizational consequences to ensure quality.

Keywords: Cancer du col de l’utérus; Cervix cancer; Curiethérapie guidée par l’image; Débit de dose pulsé; Image-guided adaptive brachytherapy; Pulsed-dose rate.

Publication types

  • Review

MeSH terms

  • Brachytherapy / adverse effects
  • Brachytherapy / instrumentation
  • Brachytherapy / methods*
  • Combined Modality Therapy
  • Dose Fractionation, Radiation
  • Equipment Design
  • Female
  • Humans
  • Neoadjuvant Therapy / methods
  • Organs at Risk
  • Quality Assurance, Health Care
  • Quality Control
  • Radiation Injuries / prevention & control
  • Radiation Protection
  • Radioisotopes / administration & dosage
  • Radiotherapy Dosage
  • Radiotherapy, Image-Guided
  • Treatment Outcome
  • Uterine Cervical Neoplasms / radiotherapy*
  • Uterine Cervical Neoplasms / surgery

Substances

  • Radioisotopes