Silver-mediated decarboxylative C-S cross-coupling of aliphatic carboxylic acids under mild conditions

Org Lett. 2014 Sep 5;16(17):4586-9. doi: 10.1021/ol502144c. Epub 2014 Aug 25.

Abstract

A silver-mediated decarboxylative C-S cross-coupling reaction of aliphatic carboxylic acid is described. This reaction occurs smoothly under mild conditions and shows good tolerance of functional groups. It provides an alternative approach for the synthesis of alkyl aryl sulfides.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carboxylic Acids / chemistry*
  • Catalysis
  • Decarboxylation
  • Molecular Structure
  • Potassium Compounds / chemistry
  • Silver Nitrate / chemistry*
  • Sulfates / chemistry
  • Sulfides / chemical synthesis*
  • Sulfides / chemistry

Substances

  • Carboxylic Acids
  • Potassium Compounds
  • Sulfates
  • Sulfides
  • potassium persulfate
  • Silver Nitrate