Black Currant Nectar Reduces Muscle Damage and Inflammation Following a Bout of High-Intensity Eccentric Contractions

J Diet Suppl. 2016;13(1):1-15. doi: 10.3109/19390211.2014.952864. Epub 2014 Aug 25.

Abstract

This investigation determined the efficacy of black currant nectar (BCN) in reducing symptoms of exercise-induced muscle damage (EIMD). Sixteen college students were randomly assigned to drink either 16 oz of BCN or a placebo (PLA) twice a day for eight consecutive days. A bout of eccentric knee extensions (3 × 10 sets @ 115% of 1RM) was performed on the fourth day. Outcome measures included muscle soreness (subjective scale from 0 to 10) and blood markers of muscle damage (creatine kinase, CK), inflammation (interleukin-6, IL-6), and oxygen radical absorbance capacity (ORAC). Although there were no differences in reported soreness between groups, consumption of BCN reduced CK levels at both 48 (PLA = 82.13% vs. BCN = -6.71%, p = .042) and 96 h post exercise (PLA = 74.96% vs. BCN = -12.11%, p = .030). The change in IL-6 was higher in the PLA group (PLA = 8.84% vs. BCN = -6.54%, p = .023) at 24 h post exercise. The change in ORAC levels was higher in the treatment group (BCN = 2.68% vs. PLA = -6.02%, p = .039) at 48 h post exercise. Our results demonstrate that consumption of BCN prior to and after a bout of eccentric exercise attenuates muscle damage and inflammation.

Keywords: anthocyanins; antioxidants; inflammation; muscle damage; oxidative damage.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Anthocyanins / pharmacology
  • Anthocyanins / therapeutic use
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use
  • Creatine Kinase / blood
  • Double-Blind Method
  • Exercise / physiology*
  • Female
  • Fruit / chemistry*
  • Fruit and Vegetable Juices
  • Humans
  • Inflammation / blood
  • Inflammation / etiology
  • Inflammation / prevention & control*
  • Interleukin-6 / blood
  • Male
  • Muscle Contraction
  • Muscle, Skeletal / drug effects*
  • Muscle, Skeletal / metabolism
  • Muscle, Skeletal / pathology
  • Musculoskeletal Pain / etiology
  • Musculoskeletal Pain / prevention & control*
  • Oxidative Stress / drug effects
  • Phytotherapy
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*
  • Ribes / chemistry*
  • Young Adult

Substances

  • Anthocyanins
  • Anti-Inflammatory Agents
  • Antioxidants
  • Interleukin-6
  • Plant Extracts
  • Creatine Kinase