Liver cell proliferation and tumor promotion by phenobarbital: relevance for humans?

Arch Toxicol. 2014 Oct;88(10):1771-2. doi: 10.1007/s00204-014-1331-6. Epub 2014 Aug 21.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Animals
  • Carcinogens / toxicity*
  • Cell Proliferation / drug effects*
  • Cocarcinogenesis
  • Constitutive Androstane Receptor
  • Humans
  • Liver Neoplasms / chemically induced*
  • Liver Neoplasms / genetics
  • Liver Neoplasms / metabolism
  • Liver Neoplasms / pathology
  • Phenobarbital / toxicity*
  • Receptors, Cytoplasmic and Nuclear / genetics
  • Receptors, Cytoplasmic and Nuclear / metabolism*

Substances

  • Carcinogens
  • Constitutive Androstane Receptor
  • Receptors, Cytoplasmic and Nuclear
  • Phenobarbital