Factors associated with malnutrition in patients with head and neck cancer

Acta Otolaryngol. 2014 Oct;134(10):1079-85. doi: 10.3109/00016489.2014.906750. Epub 2014 Aug 18.

Abstract

Conclusions: Comorbidities as well as T classification were the primary determinants for the nutritional status of patients with head and neck cancer.

Objectives: We aimed to elucidate the underlying conditions of malnutrition in patients with head and neck cancer.

Methods: We retrospectively reviewed 726 patients diagnosed with head and neck cancer between 2004 and 2013. Associations between malnutrition and clinical parameters were assessed using univariate and multivariate analyses.

Results: Median body mass index was 21.5 (range 11.6-38.0). According to World Health Organization criteria, the nutritional status of these patients was classified into four groups: underweight (18%), normal (63%), overweight (17%), and obese (1%). Comorbidities were detected in 40% of patients. Multivariate analysis revealed the following factors to be independent factors associated with malnutrition: advanced T stage, metachronous cancer, collagen disease, gastrointestinal disease, and pulmonary disease.

Keywords: Body mass index; comorbidity; metachronous cancer; nutrition.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Analysis of Variance
  • Body Mass Index*
  • Cohort Studies
  • Comorbidity
  • Female
  • Head and Neck Neoplasms / diagnosis*
  • Head and Neck Neoplasms / epidemiology*
  • Head and Neck Neoplasms / therapy
  • Humans
  • Japan / epidemiology
  • Logistic Models
  • Male
  • Malnutrition / diagnosis*
  • Malnutrition / epidemiology*
  • Middle Aged
  • Multivariate Analysis
  • Nutritional Status
  • Prevalence
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Sex Distribution
  • Young Adult