Comparison of clinical outcomes for 40 necrotic immature permanent incisors treated with calcium hydroxide or mineral trioxide aggregate apexification/apexogenesis

J Formos Med Assoc. 2015 Feb;114(2):139-46. doi: 10.1016/j.jfma.2014.06.005. Epub 2014 Aug 11.

Abstract

Background/purpose: Traumatic injury often results in pulp necrosis of immature permanent incisors in children. This study compared clinical outcomes for 40 necrotic immature permanent incisors treated with calcium hydroxide [Ca(OH)2] or mineral trioxide aggregate (MTA) apexification/apexogenesis.

Methods: Forty necrotic open-apex incisors from 40 children aged 6.5-10 years were divided evenly into four groups with each group containing teeth of similar type and similar root apex width in patients of similar age. Group 1 incisors were treated with ultrasonic filing and MTA placement; Group 2 were treated with ultrasonic filing and Ca(OH)2 medication; Group 3 were treated with hand filing and MTA placement; and Group 4 were treated with hand filing and Ca(OH)2 medication.

Results: Group 1 incisors needed the shortest mean duration (5.4 ± 1.1 weeks) for apical hard tissue barrier formation, followed by Group 3 incisors (7.8 ± 1.8 weeks), Group 2 incisors (11.3 ± 1.3 weeks), and Group 4 incisors (13.1 ± 1.5 weeks). Group 1 incisors had a significantly shorter mean elongated root length (2.1 ± 0.2 mm) after treatment than Group 2 incisors (3.5 ± 0.3 mm, p < 0.001), and Group 3 incisors had a significantly shorter mean elongated root length (2.1 ± 0.1 mm) after treatment than Group 4 incisors (3.7 ± 0.3 mm, p < 0.001).

Conclusion: Necrotic open-apex incisors treated with ultrasonic filing plus MTA placement need the shortest mean duration for apical hard tissue barrier formation. For elongation of apical root length, Ca(OH)2 apexification/apexogenesis is better than MTA apexification/apexogenesis, regardless if either ultrasonic or hand filing are used.

Keywords: apexification; apexogenesis; calcium hydroxide; mineral trioxide aggregate; sodium hypochlorite; ultrasonics.

Publication types

  • Comparative Study

MeSH terms

  • Aluminum Compounds / therapeutic use*
  • Apexification / methods*
  • Calcium Compounds / therapeutic use*
  • Calcium Hydroxide / therapeutic use*
  • Child
  • Dental Pulp Necrosis / therapy*
  • Drug Combinations
  • Female
  • Humans
  • Incisor / injuries*
  • Male
  • Oxides / therapeutic use*
  • Root Canal Filling Materials / therapeutic use
  • Silicates / therapeutic use*
  • Tooth Root / diagnostic imaging*

Substances

  • Aluminum Compounds
  • Calcium Compounds
  • Drug Combinations
  • Oxides
  • Root Canal Filling Materials
  • Silicates
  • mineral trioxide aggregate
  • Calcium Hydroxide