Automatic lesion detection in capsule endoscopy based on color saliency: closer to an essential adjunct for reviewing software

Gastrointest Endosc. 2014 Nov;80(5):877-83. doi: 10.1016/j.gie.2014.06.026. Epub 2014 Aug 1.

Abstract

Background: The advent of wireless capsule endoscopy (WCE) has revolutionized the diagnostic approach to small-bowel disease. However, the task of reviewing WCE video sequences is laborious and time-consuming; software tools offering automated video analysis would enable a timelier and potentially a more accurate diagnosis.

Objective: To assess the validity of innovative, automatic lesion-detection software in WCE.

Design/intervention: A color feature-based pattern recognition methodology was devised and applied to the aforementioned image group.

Setting: This study was performed at the Royal Infirmary of Edinburgh, United Kingdom, and the Technological Educational Institute of Central Greece, Lamia, Greece.

Materials: A total of 137 deidentified WCE single images, 77 showing pathology and 60 normal images.

Results: The proposed methodology, unlike state-of-the-art approaches, is capable of detecting several different types of lesions. The average performance, in terms of the area under the receiver-operating characteristic curve, reached 89.2 ± 0.9%. The best average performance was obtained for angiectasias (97.5 ± 2.4%) and nodular lymphangiectasias (96.3 ± 3.6%).

Limitations: Single expert for annotation of pathologies, single type of WCE model, use of single images instead of entire WCE videos.

Conclusion: A simple, yet effective, approach allowing automatic detection of all types of abnormalities in capsule endoscopy is presented. Based on color pattern recognition, it outperforms previous state-of-the-art approaches. Moreover, it is robust in the presence of luminal contents and is capable of detecting even very small lesions.

MeSH terms

  • Capsule Endoscopy / methods*
  • Case-Control Studies
  • Color*
  • Diagnosis, Computer-Assisted*
  • Duodenal Diseases / diagnosis*
  • Electronic Data Processing
  • Gastrointestinal Hemorrhage / diagnosis
  • Humans
  • Ileal Diseases / diagnosis*
  • Image Processing, Computer-Assisted
  • Intestinal Polyps / diagnosis
  • Jejunal Diseases / diagnosis*
  • Lymphangiectasis, Intestinal / diagnosis
  • Pattern Recognition, Automated*
  • Peptic Ulcer / diagnosis
  • ROC Curve
  • Reproducibility of Results
  • Software*
  • Stomatitis, Aphthous / diagnosis