Long-term outcome after adjacent two-level anterior cervical discectomy and fusion using stand-alone plasmaphore-covered titanium cages

J Neurol Surg A Cent Eur Neurosurg. 2015 May;76(3):199-204. doi: 10.1055/s-0034-1382782. Epub 2014 Jul 29.

Abstract

Background: Reports on long-term outcome of stand-alone contiguous two-level anterior cervical discectomy and fusion (ACDF) using stand-alone Plasmaphore-coated titanium cages (PCTCs) are rare, and data on follow-ups > 3 years are missing.

Objective: To evaluate the long-term outcome of adjacent two-level microsurgical ACDF using stand-alone PCTC.

Patients/material and methods: A total of 33 consecutive patients presented with cervical degenerative disc disease (DDD) underwent contiguous two-level ACDF. Clinical long-term evaluation (mean: 61 ± 14 months) included documentation of neurologic deficits (motor deficits, sensory deficits, reflex status, and gait disturbance), neck pain, and radicular pain. Functional outcome was measured using the Odom criteria, patient-perceived outcome, and evaluation of work status. Radiographs were evaluated to assess intervertebral disc height, subsidence, level of fusion, sagittal balance, and implant position.

Results: Surgery was performed at levels C5-C6 and C6-C7 in 30 patients and at C4-C5 and C5-C6 in 3 (mean age: 50.1 ± 7.7 years). Symptoms and neurologic deficits improved as follows: neurologic deficits (pre: 100%; post: 36%), radicular pain (pre: 85%; post: 15%), and neck pain (pre: 94%; post: 33%). Excellent and good functional and subjective outcome was noted in 75%. Cage subsidence was found to be more prominent in the lower (52%) than the upper (36%) mobile cervical segment. Two-level fusion was documented in most patients (n = 29 [88%]). Kyphotic deformity occurred in two cases (n = 2 [6%]).

Conclusions: Stand-alone contiguous two-level ACDF using PCPT proved to be effective, yielding good long-term clinical and functional outcomes. The relatively high rate of subsidence did not affect the good clinical and functional long-term outcome.

MeSH terms

  • Adult
  • Aged
  • Cervical Vertebrae / surgery*
  • Diskectomy / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Internal Fixators*
  • Intervertebral Disc Degeneration / surgery*
  • Male
  • Middle Aged
  • Spinal Fusion / methods*
  • Titanium
  • Treatment Outcome

Substances

  • Titanium