Serial magnetic resonance imaging changes in sporadic Creutzfeldt-Jakob disease with valine homozygosity at codon 129 of the prion protein gene

JAMA Neurol. 2014 Sep;71(9):1186-7. doi: 10.1001/jamaneurol.2014.548.

Authors

Fumiko Furukawa¹, Satoru Ishibashi¹, Nobuo Sanjo¹, Hiroshi Yamashita², Hidehiro Mizusawa³

Affiliations

¹ Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Tokyo, Japan.
² Department of Neurology, Hiroshima City Asa Hospital, Tokyo, Japan.
³ Department of Neurology and Neurological Science, Tokyo Medical and Dental University, Tokyo, Japan3currently with The National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan.

PMID: 25070174
DOI: 10.1001/jamaneurol.2014.548

No abstract available

Publication types

Case Reports

MeSH terms

Cerebellar Cortex / metabolism
Codon / genetics
Creutzfeldt-Jakob Syndrome / genetics*
Creutzfeldt-Jakob Syndrome / metabolism
Creutzfeldt-Jakob Syndrome / pathology*
Creutzfeldt-Jakob Syndrome / physiopathology
Diffusion Magnetic Resonance Imaging
Electroencephalography
Homozygote
Humans
Male
Middle Aged
Positron-Emission Tomography
Prions / genetics*
Thalamus / metabolism
Thalamus / pathology*
Valine / genetics

Substances

Codon
Prions
Valine

Supplementary concepts

Creutzfeldt-Jakob Disease, Sporadic