Reaching low density lipoprotein cholesterol targets

Curr Med Res Opin. 2014 Oct;30(10):1967-9. doi: 10.1185/03007995.2014.941979. Epub 2014 Jul 31.

Abstract

Cardiovascular disease is a major health problem and within the leading causes of death worldwide. Low-density lipoprotein cholesterol (LDL-C) is strongly associated with the development and progression of cardiovascular disease and is among the main targets of lipid lowering therapy. Despite the various lipid lowering agents for the management of hyperlipidemia, a significant number of patients do not reach their LDL-C target goals. Data from studies in various world regions identify an often poor achievement of LDL-C goals, especially in high risk patient groups. The causes of this suboptimal management of hyperlipidemia are multifactorial and measures should be taken in order to identify and address these shortcomings in dyslipidemia therapy.

Keywords: Cardiovascular disease; Lipid lowering therapy; Low density lipoprotein cholesterol; Risk factors.

Publication types

  • Editorial

MeSH terms

  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / prevention & control*
  • Cholesterol, LDL / blood*
  • Dyslipidemias* / blood
  • Dyslipidemias* / complications
  • Humans
  • Hypolipidemic Agents / therapeutic use*
  • Risk Factors

Substances

  • Cholesterol, LDL
  • Hypolipidemic Agents