Abstract
The efficacy of Triazavirin against the tick-borne encephalitis virus was estimated in the sensitive cell culture vs. the active drug Ribavirin. In a concentration of 128 mcg/ml Triazavirin was shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture.
MeSH terms
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Animals
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Antiviral Agents / chemical synthesis
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Antiviral Agents / pharmacology*
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Azoles / chemical synthesis
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Azoles / pharmacology*
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Cell Line
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Encephalitis Viruses, Tick-Borne / drug effects*
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Encephalitis Viruses, Tick-Borne / physiology
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Epithelial Cells / cytology
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Epithelial Cells / drug effects*
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Epithelial Cells / virology
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Kidney / cytology
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Kidney / drug effects*
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Kidney / virology
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Ribavirin / pharmacology
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Swine
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Triazines / chemical synthesis
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Triazines / pharmacology*
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Triazoles
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Virus Replication / drug effects
Substances
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Antiviral Agents
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Azoles
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Triazines
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Triazoles
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Ribavirin
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riamilovir