Chiral dirhodium(II) carboxylates and carboxamidates as effective chemzymes in asymmetric synthesis of three-membered carbocycles

Frady G Adly; Ashraf Ghanem

doi:10.1002/chir.22347

Chiral dirhodium(II) carboxylates and carboxamidates as effective chemzymes in asymmetric synthesis of three-membered carbocycles

Chirality. 2014 Nov;26(11):692-711. doi: 10.1002/chir.22347. Epub 2014 Jul 15.

Authors

Frady G Adly¹, Ashraf Ghanem

Affiliation

¹ Chirality program, Faculty of ESTEM, University of Canberra, ACT, Australia.

PMID: 25042238
DOI: 10.1002/chir.22347

Abstract

In this review the recent advances in the utilization of two of the most important classes of dirhodium(II) paddlewheel complexes, dirhodium(II) carboxylates and carboxamidates, as chemzymes in inter- and intramolecular asymmetric cyclopropanation, as well as cyclopropenation reactions are discussed.

Keywords: asymmetric; cyclopropanation; cyclopropenation; dirhodium(II) carboxamidates; dirhodium(II) carboxylates; paddlewheel.